TESIS DOCTORALES LEIDAS 2015 / 2016

TÍTULOAUTORFECHADIRECCIÓNURL
Intestinal anti-inflammatory activity of probiotics in experimental models of colitis: impact of cell viability and role of microRNAsAlba Rodríguez Nogales14/07/2015Julio Gálvez Peralta

Mª Elena Rodríguez Cabezas

Carlo Riccardi
Medicinal plants from Andalusia: potential use as intestinal antiinflammatory agentsFrancesca Algieri30/10/2015Julio Gálvez Peralta

Mª Elena Rodríguez Cabezas

Mª Pilar Utrilla Navarro
miRNA-146a regula la interacción entre células epiteliales intestinales, microbiota y estímulos inflamatoriosAndrea AnzolaJulio 2016Raquel González Pérez

Olga Martínez Augustín

Antonio Zarzuelo Zurita
Epidemiological Studies on Zoonotic Leishmaniasis and New Trial for Studying the Effects of Melatonin on the parasites.Ehab Kothb Abd Elghany ElmahallawayNov 2016Ahmad Agil
Programa de Conciliación de la Medicación en Medicina Interna: Transición segura entre niveles asistencialesSusana Belda Rustarazo05/02/2016Julio Gálvez Peralta
Estudio de la utilización de fármacos antidepresivos en el ámbito de la atención primaria de AlmeríaMaría del Carmen González LópezDiciembre 2015Esperanza del Pozo Gavilán

1. López-Posadas R; Mascaraque C; *González R; Suárez MD; Zarzuelo A; Martínez-Augustín O; Sánchez de Medina F. The bisphosphonate pamidronate is an intestinal anti-inflammatory agent in rat and mouse experimental colitis. Inflammatory Bowel Disease 2016 Nov; 22(11): 2549-2561.

2. Nieto FR, Clark AK, Grist J, Hathway GJ, Chapman V, Malcangio M. Neuron-immune mechanisms contribute to pain in early stages of arthritis. J Neuroinflammation 13(1):96 2016

3. Romero M; Jiménez R; Toral M; León-Gómez M, Gómez-Guzmán M; Sánchez M; Zarzuelo MJ; Rodríguez-Gómez I, Rath G, Tamargo J; Pérez-Vizcaíno F; Dessy C; Duarte J. Vascular and central activation of Peroxisome Proliferator-Activated Receptor-β attenuates angiotensin II-induced hypertension. Role of RGS-5. J Pharmacol Exp Ther.358 (1), 151-163, 2016

4. Toral M, Romero M, Jiménez R, Robles-Vera I, Tamargo J, Martínez MC, Pérez-Vizcaíno F, Duarte J. Role of UCP2 in the protective effects of PPARβ/δ activation on lipopolysaccharide-induced endothelial dysfunction. Biochem Pharmacol. 2016 Jun 15;110-111:25-36.

5. Masocha W, Gonzalez GL, Agil A. Distinguishing subgroups among μ-opioid receptor agonists using Na+,K+-ATPase as an effector mechanism. European Journal of Pharmacology. 2016. 5;774:43-9.

6. Agil A, Elmahallawy EK, Rodríguez-Ferrer JM, Adem A, Bastaki SM, Al-Abbadi I, Fino Solano YA, Navarro-Alarcón M.Melatonin increases intracellular calcium in the liver, muscle, white adipose tissues and pancreas of diabetic obese rats. Food & Function. 2015. 5;6(8):2671-8.

7. Campos D, Hernández-Torres JJ, Agil A, Comino M, López JC, Macías V, Campoy C.Analysis of food advertising to children on Spanish television: probing exposure to television marketing. Arch Med Sci. 2016.1;12(4):799-807.

8. Agil A, El-Hammadi M, Jiménez-Aranda A, Tassi M, Abdo W, Fernández-Vázquez G, Reiter RJ. Melatonin Reduces Hepatic Mitochondrial Dysfunction in Diabetic Obese Rats. Journal of Pineal Research. 2015. 59(1):70-9.

9. Elmahallawy EK, Cuadras-Moronta E, Liébana-Martos MC, Rodríguez-Granger JM, Sampedro-Martínez A, Agil A, Navarro-Mari JM, Bravo-Soto J, Gutierrez-Fernández J Seroprevalence of Leishmania infection among asymptomatic renal transplant recipients from southern Spain.. Transpl Infect Dis. 2015.17(6):795-9. doi: 10.1111/tid.12444.

10. Román S, Agil A, Perán M, Alvaro-Galue E, Ruiz-Ojeda FG, Marchal JA. Brown adipose tissue and novel therapeutic approaches to treat metabolic disorders. Translational Research. (2015). 165(4):464-79.

11. Elmahallawy EK, Agil A. Curr Pharm Des. Treatment of Leishmaniasis: A Review and Assessment of Recent Research. 2015. 21(17):2259-75.

12. Elmahallawy EK, Luque JO, Aloweidi AS, Fernández JG, Martínez AS, Rodriguez-Granger J, Kaki A, Agil A. Potential relevance of melatonin against some infectious agents: A Review and Assessment of Recent Research. Curr Med Chem. 2015. 22(33):3848-61.

13. Berglund SK, García-Valdés L, Torres-Espinola FJ, Segura MT, Martínez-Zaldívar C, Aguilar MJ, Agil A, Lorente JA, Florido J, Padilla C, Altmäe S, Marcos A, López-Sabater MC, Campoy C; PREOBE team. Maternal, fetal and perinatal alterations associated with obesity, overweight and gestational diabetes: an observational cohort study (PREOBE). BMC Public Health. 2016. 1; 16(1).

14. Torres-Espínola FJ, Altmäe S, Segura MT, Jerez A , Anjos Tania, Chisaguano M, López- Sabater MC, Entrala C , Alvarez JC, Agil A , Florido J, Catena A, Pérez-García M, Campoy M. Maternal PPARG Pro12Ala polymorphism is associated with infant’s neurodevelopmental outcomes at 18 months of age. Early Human Development. 2015. 91 457–462.

15. Araújo DF, Guerra GC, Júnior RF, Antunes de Araújo A, Antonino de Assis PO, Nunes de Medeiros A, Formiga de Sousa YR, Pintado MM, Gálvez J, Queiroga RC. Goat whey ameliorates intestinal inflammation on acetic acid-induced colitis in rats. J Dairy Sci. 2016 Dec;99(12):9383-9394.

16. Rodriguez-Nogales A, Algieri F, De Matteis L, Lozano-Perez AA, Garrido-Mesa J, Vezza T, de la Fuente JM, Cenis JL, Gálvez J, Rodriguez-Cabezas ME. Intestinal anti-
inflammatory effects of RGD-functionalized silk fibroin nanoparticles in trinitrobenzenesulfonic acid-induced experimental colitis in rats. Int J Nanomedicine. 2016 Nov 10;11:5945-5958.

17. Abiodun OO, Rodríguez-Nogales A, Algieri F, Gomez-Caravaca AM, Segura-Carretero A, Utrilla MP, Rodriguez-Cabezas ME, Galvez J. Antiinflammatory and immunomodulatory activity of an ethanolic extract from the stem bark of Terminalia catappa L. (Combretaceae): In vitro and in vivo evidences. J Ethnopharmacol. 2016 Nov 4;192:309-319. doi: 10.1016/j.jep.2016.07.056.

18. Rodriguez-Nogales A, Lozano-Pérez AA, Aznar-Cervantes SD, Algieri F, Garrido-Mesa J, Garrido-Mesa N, Vezza T, Utrilla MP, Cenis JL, Rodríguez-Cabezas ME, Gálvez J. Effect of aqueous and particulate silk fibroin in a rat model of experimental colitis. Int J Pharm. 2016 Sep 10;511(1):1-9. doi: 10.1016/j.ijpharm.2016.06.120.

19. Bribi N, Algieri F, Rodriguez-Nogales A, Vezza T, Garrido-Mesa J, Utrilla MP, Del Mar Contreras M, Maiza F, Segura-Carretero A, Rodriguez-Cabezas ME, Gálvez J. Intestinal anti-inflammatory effects of total alkaloid extract from Fumaria capreolata in the DNBS model of mice colitis and intestinal epithelial CMT93 cells. Phytomedicine. 2016 Aug 15;23(9):901-13. doi: 10.1016/j.phymed.2016.05.003.

20. Martín M, Rodríguez-Nogales A, Garcés V, Gálvez N, Gutiérrez L, Gálvez J, Rondón D, Olivares M, Dominguez-Vera JM. Magnetic study on biodistribution and biodegradation of oral magnetic nanostructures in the rat gastrointestinal tract. Nanoscale. 2016 Aug 11;8(32):15041-7. doi: 10.1039/c6nr04678a.

21. Algieri F, Rodriguez-Nogales A, Vezza T, Garrido-Mesa J, Garrido-Mesa N, Utrilla MP, González-Tejero MR, Casares-Porcel M, Molero-Mesa J, Del Mar Contreras M, Segura- Carretero A, Pérez-Palacio J, Diaz C, Vergara N, Vicente F, Rodriguez-Cabezas ME, Galvez J. Anti-inflammatory activity of hydroalcoholic extracts of Lavandula dentata L. and Lavandula stoechas L. J Ethnopharmacol. 2016 Aug 22;190:142-58. doi: 10.1016/j.jep.2016.05.063.

22. Pérez Del Palacio J, Díaz C, de la Cruz M, Annang F, Martín J, Pérez-Victoria I, González- Menéndez V, de Pedro N, Tormo JR, Algieri F, Rodriguez-Nogales A, Rodríguez-Cabezas ME, Reyes F, Genilloud O, Vicente F, Gálvez J. High-Throughput Screening Platform for the Discovery of New Immunomodulator Molecules from Natural Product Extract Libraries. J Biomol Screen. 2016 Jul;21(6):567-78. doi: 10.1177/1087057116635517.

23. Hidalgo-Cantabrana C, Algieri F, Rodriguez-Nogales A, Vezza T, Martínez-Camblor P, Margolles A, Ruas-Madiedo P, Gálvez J. Effect of a Ropy Exopolysaccharide-Producing Bifidobacterium animalis subsp. lactis Strain Orally Administered on DSS-Induced Colitis Mice Model. Front Microbiol. 2016 Jun 9;7:868.

24. Vezza T, Rodríguez-Nogales A, Algieri F, Utrilla MP, Rodriguez-Cabezas ME, Galvez J. Flavonoids in Inflammatory Bowel Disease: A Review. Nutrients. 2016 Apr 9;8(4):211.

25. Algieri F, Rodriguez-Nogales A, Garrido-Mesa J, Camuesco D, Vezza T, Garrido-Mesa N, Utrilla P, Rodriguez-Cabezas ME, Pischel I, Galvez J. Intestinal anti-inflammatory activity of calcium pyruvate in the TNBS model of rat colitis: Comparison with ethyl pyruvate. Biochem Pharmacol. 2016 Mar 1;103:53-63.

26. Romero M, Toral M, Gómez-Guzmán M, Jiménez R, Galindo P, Sánchez M, Olivares M, Gálvez J, Duarte J. Antihypertensive effects of oleuropein-enriched olive leaf extract in spontaneously hypertensive rats. Food Funct. 2016 Jan;7(1):584-93.

27. Betim Cazarin CB, Rodriguez-Nogales A, Algieri F, Utrilla MP, Rodríguez-Cabezas ME, Garrido-Mesa J, Guerra-Hernandez E, de Campos Braga PA, Reyes Reyes FG, Marostica MR Jr, Galvez J. Intestinal anti-inflammatory effects of Passiflora edulis peel in the dextran soidum sulphate model of mouse colitis. J Funct Foods. 2016; 26: 565 – 576. doi:10.1016/j.jff.2016.08.020

28. – Talhaoui N, Vezza T, Gómez-Caravaca AM, Fernández-Gutiérrez A, Galvez J, Segura- Carretero A. Phenolic compounds and in vitro immunomodulatory properties of three Andalusian olive leaf extracts. J Funct Foods. 2016; 26: 270 – 277.

29. Entrena JM, Sánchez-Fernández C, Nieto FR, González-Cano R, Yeste S, Cobos EJ, Baeyens JM. Sigma-1 receptor agonism promotes mechanical allodynia after priming the nociceptive system with capsaicin. Scientific Rep 6: 37835, 2016

30. Mediavilla-García, Cristina; Martin-Signes, Mar; Risco-Acedo, Severiano. Role Of Anterior Piriform Cortex In The Acquisition Of Conditioned Flavour Preference. Scientific Reports, 6: 33365. 2016.

31. Mediavilla-García, Cristina; Martin-Signes, Mar; Risco-Acedo, Severiano. “Orexin A in the ventral tegmental area enhances saccharin-induced conditioned flavor preference in a dose-dependent manner” Intrinsic Activity, 2016, 4 (Suppl. 2):A18.69

32. Jiménez-García AM, Ruíz-Leyva L, Cendán CM, Torres C, Papini MR, Morón I. Hypoalgesia Induced by Reward Devaluation in Rats. PLoS One. 2016 Oct 20;11(10):e0164331

33. Pardo Cabello AJ, Del Pozo Gavilán E, Gómez Jiménez FJ, Mota Rodríguez C, Luna Del Castillo Jde D, Puche Cañas E. Drug-related mortality among inpatients: a retrospective observational study. Eur J Clin Pharmacol. 2016 Jun;72(6):731-6

34. Bonilla García JL, López Martín R, Cortiñas Saenz M, Del Pozo Gavilán E. Patrones de infección asociados a los cuidados de salud en el paciente crítico postquirúrgico. Rev. Soc. Esp. Dolor 2017.